It starts in the area of Frosinone from the confluence between the Liri, which first crosses Abruzzo and Lazio, and the Gari, which rises at Cassino and is often called Liri-Garigliano.

For the ancient Italic peoples it was a sacred river. On the shores, they erected sanctuaries such as the Demetra and Teano one.

The longest river of Southern Italy with its 175 kilometres rises in Molise, at Rocchetta a Volturno and runs for a long way in the Apennine region, of which, after the Ponte 25 archi, marks the border with Campania.

It rises at the foot of Mounts Trebulani, at 86 meters above sea level, in the territory of Calvi Risorta.

Although its name derives from the Oscan word tifata, which means holm oak, Mount Tifata is largely barren, except for the woods surrounding the northern side.

It is an artificial lake, created in the 1960s to power the electricity station of Capriati al Volturno.